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In silico toxicity prediction is a method that can be used to evaluate the toxicity
profile of a compound even before it is synthesized and thus to concentrate finite
resources and energy on those compunds most likely to succeed. The result can
dramaticlly lower costs and reduce cycle time for pharmaceutical R & D.<br>
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Strand Genomics has developed a model to predict the HERG binding ability of a
drug. HERG conducts a repolarising potassium current (Ikr) which is critical in
maintaining normal cardiac rhythm. <br>
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